Date: Tuesday, Dec. 7, 08:00 PST / 11:00 EST / 16:00 GMT / 17:00 CET
Presented by SelectScience
A comprehensive picture of somatic cell clonal evolution driving tumorigenesis is not possible with bulk sequencing strategies that fail to uncover rare alleles. Single-cell analysis provides the fundamental unit of resolution to define this evolution, but existing methods to amplify the genomes of single cells suffer from poor genomic coverage, uniformity, and allelic balance. The ResolveDNA™ amplification utilizes primary template-directed amplification (PTA) to overcome each of these shortcomings, providing unprecedented accuracy in single nucleotide variation (SNV) and copy number variation (CNV) calling.
Join this webinar to learn how ResolveDNA™ chemistry can be used to study allelic variation at a single-cell resolution. Cells enriched from heterogenous tumors utilizing Sony cell sorters can be used upstream of the ResolveDNA™ chemistry to concomitantly improve the sensitivity of variant allele detection. Strategies for cell sorting of different samples into multi-well PCR plate formats for genomic amplification studies will be discussed.
Learning objectives:
Certificate of attendance
All webinar participants can request a certificate of attendance and a learning outcomes summary document for continuing education purposes
Speaker
Dr. Jon Zawistowski
Senior Director of R&D
BioSkryb Genomics, Inc.
Date: Tuesday, Dec. 7, 08:00 PST / 11:00 EST / 16:00 GMT / 17:00 CET
Register NOWSource: sonybiotechnology.com